HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl L-tert-leucinate hydrochloride → (S)-2-[(5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carbonyl)-amino]-3,3-dimethyl-butyric acid methyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl L-tert-leucinate hydrochloride | HCID 16217630 | — |
| Edukt | 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid | HCID 71087346 | — |
| Produkt | (S)-2-[(5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carbonyl)-amino]-3,3-dimethyl-butyric acid methyl ester | HCID 71087494 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethyloxy-pyridine-2-carboxylic acid (Example 42a) and 3-methyl-L-valine methyl ester hydrochloride (1:1) (CAN 63038-27-7) as starting materials, MS (ESI) 361.3 (M+H)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09321727B2 |
| Quelldatensatz | uspto-grants-2016_04 |
| ORD ID | ord-f4bfa59bffeb45919fcded4a93b96810 |
| Quellennotiz | uspto-grants-2016_04 |