HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid | HCID 4270263 | — |
| Edukt | 4-Chloro-3-(pyridin-2-yl)aniline | HCID 40151925 | — |
| Produkt | N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamide | HCID 58614761 | — |
Reaktionsschritte
50 mg of 4-chloro-3-(pyridin-2-yl)aniline was coupled to 1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid via Procedure G. The product was purified on reverse phase HPLC to yield N-(4-chloro-3-(pyridin-2-yl)phenyl)-1-(4-fluorophenyl)-5-methyl-1H-pyrazole-4-carboxamide. MS (Q1) 407.0 (M)+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09321761B2 |
| Quelldatensatz | uspto-grants-2016_04 |
| ORD ID | ord-21a1045fadf041578ac9f60371201b3a |
| Quellennotiz | uspto-grants-2016_04 |