HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrazine hydrate (1:1) → 6-Chloro-1,3-dihydroindol-2-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Edukt | 6-Chloroindoline-2,3-dione | HCID 241331 | — |
| Edukt | Sodium ethoxide | HCID 2723922 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 6-Chloro-1,3-dihydroindol-2-one | HCID 736344 | 42,5% |
Reaktionsschritte
Reaction of 36.2 g of 6-chloroisatin with hydrazine hydrate followed by sodium ethoxide in ethanol, substantially according to C above, afforded 14.2 g of 6-chloro-2-oxindole, m.p. 196°-198° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04556672 |
| Quelldatensatz | uspto-grants-1985_12 |
| ORD ID | ord-31d493f9b72643508f92d4b97d9de615 |
| Quellennotiz | uspto-grants-1985_12 |