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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 64090Erstellt: 24. Oktober 2026

Cyclopropanesulfonyl chloride → Odm-203

https://huagongshe.com/de/reaction/64090

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktCyclopropanesulfonyl chlorideHCID 2760919—
EduktN-(2',4'-difluoro-5-(5-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)-biphenyl-3-yl)acetamideHCID 71554235—
ProduktOdm-203HCID 71554322—

Reaktionsschritte

The compound was prepared from the compound of Example 1 using the procedures of Example 2 and cyclopropane sulfonyl chloride. 1H NMR (300 MHz, DMSO-d6): δ 10.29 (s, 1H), 8.88 (s, 1H), 8.23 (s, 1H), 8.0 (s, 1H), 7.96 (s, 1H), 7.76-7.64 (m, 3H), 7.6 (s, 2H), 7.5-7.46 (m, 2H), 7.3-7.25 (m, 1H), 3.88 (s, 3H), 2.88-2.85 (m, 1H), 1.02-1.0 (m, 4H); LC-MS (ESI): Calculated mass: 505.54; Observed mass: 506.1 [M+H]+ (rt: 1.517 min).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09447091B2
Quelldatensatzuspto-grants-2016_09
ORD IDord-c8573def410d4e758007e3315e3c7c2a
Quellennotizuspto-grants-2016_09