Cyclopropanesulfonyl chloride → N-(2',4'-difluoro-5-(5-(1-(3-hydroxy-3-methylbutyl)-1H-1,2,3-triazol-4-yl)-1H-benzo[d]imidazol-1-yl)biphenyl-3-yl)cyclopropanesulfonamide

Beteiligte Stoffe

Reaktionsschritte

The compound was prepared from the compound of Example 44 using the procedures of Example 45 and cyclopropane sulfonyl chloride. 1H NMR (400 MHz, CD3OD): δ 9.09 (s, 1H), 8.47 (s, 1H), 8.30 (s, 1H), 8.0 (d, 1H), 7.83 (d, 1H), 7.69-7.60 (m, 4H), 7.17-7.10 (m, 2H), 4.62-4.58 (m, 2H), 2.78-2.69 (m, 1H), 2.17-2.13 (m, 2H), 1.29-1.15 (m, 8H), 1.10-1.02 (m, 2H); LC-MS (ESI): Calculated mass: 578.63; Observed mass: 579.2 [M+H]+ (rt: 1.449 min).

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