HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Tert-butylcyclohexane-1-carboxylic acid → n-((5s)-3-(4-(1-{4-t-Butylcyclohexylcarbonyl}-1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Tert-butylcyclohexane-1-carboxylic acid | HCID 136759 | — |
| Edukt | N-((5S)-3-(4-(1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide | HCID 20638827 | — |
| Produkt | n-((5s)-3-(4-(1-{4-t-Butylcyclohexylcarbonyl}-1,2,5,6-tetrahydropyrid-4-yl)phenyl)-2-oxooxazolidin-5-ylmethyl)acetamide | HCID 57235224 | — |
Reaktionsschritte
Using an analogous procedure to that described in Example 20, the TFA salt of Example 2 was reacted with 4-tert-butylcyclohexanecarboxylic acid in place of N-acetylglycine, to give the title compound. Yield=208 mg, 58%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06271383B1 |
| Quelldatensatz | uspto-grants-2001_08 |
| ORD ID | ord-f5e914135cfd4454a320f3dca5b9378f |
| Quellennotiz | uspto-grants-2001_08 |