HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Isobutyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione → 1-(4-aminophenyl)-3-isobutyl-3-azabicYclo[3.1.1]heptane-2,4-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Isobutyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]heptane-2,4-dione | HCID 14872630 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 1-(4-aminophenyl)-3-isobutyl-3-azabicYclo[3.1.1]heptane-2,4-dione | HCID 14872635 | — |
Reaktionsschritte
In a manner analogous to that described in Example 1, 2.0 g of 3-isobutyl-1-(4-nitrophenyl)-3-azabicyclo[3.1.1]-heptane-2,4-dione in 100 ml of ethanol are hydrogenated in the presence of 0.1 g of palladium-on-carbon and worked up. Melting point 158°-160° (from ethyl acetate/petroleum ether).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04677129 |
| Quelldatensatz | uspto-grants-1987_06 |
| ORD ID | ord-06b5ac37d5b14a14a8aa3af752d85377 |
| Quellennotiz | uspto-grants-1987_06 |