HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Methyl-4-(trifluoromethyl)benzoic acid → 2-Methyl-N-((1RS,2SR)-2-pyrrolidin-1-yl-cyclohexyl)-4-trifluoromethyl-benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Methyl-4-(trifluoromethyl)benzoic acid | HCID 22211658 | — |
| Edukt | cis-2-Pyrrolidin-1-yl-cyclohexylamine dihydrochloride | HCID 66680564 | — |
| Produkt | 2-Methyl-N-((1RS,2SR)-2-pyrrolidin-1-yl-cyclohexyl)-4-trifluoromethyl-benzamide | HCID 66682173 | — |
Reaktionsschritte
The title compound, white solid, MS: m/e=355.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclohexylamine dihydrochloride (intermediate F) and 2-methyl-4-trifluoromethyl-benzoic acid (CAS 23984-82-9).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08080541B2 |
| Quelldatensatz | uspto-grants-2011_12 |
| ORD ID | ord-36b984cebea042cf9111ee892ad8b21c |
| Quellennotiz | uspto-grants-2011_12 |