3-Hydroxy-2-naphthoic acid → 6-Hydroxy-2-naphthoic acid

Beteiligte Stoffe

Reaktionsschritte

In the carboxylation of the potassium salt of 2-hydroxynaphthalene, the initial product form is 3-hydroxy-2-naphthoic acid which subsequently rearranges in situ to form 6-hydroxy-2-naphthoic acid. It has been found that the conditions which favor the formation of 3-hydroxy-2-naphthoic acid in the Kolbe-Schmitt reaction hinder the rearrangement reaction.

Herkunft & Nachweise