HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chloro-5-ethylpyrimidine → (3R,4S)-Cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-3-fluoro-piperidin-4-yl]-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Chloro-5-ethylpyrimidine | HCID 3572763 | — |
| Edukt | HCID 68289942 | HCID 68289942 | — |
| Produkt | (3R,4S)-Cyclopropyl-[1-(5-ethyl-pyrimidin-2-yl)-3-fluoro-piperidin-4-yl]-amine | HCID 68290756 | — |
Reaktionsschritte
The title compound is prepared from cyclopropyl-[(3R,4S)-3-fluoro-piperidin-4-yl]-carbamic acid tert-butyl ester and 2-chloro-5-ethyl-pyrimidine following a procedure analogous to that described for Intermediate 73.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08822471B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-4f4240851600414389af3338dc926741 |
| Quellennotiz | uspto-grants-2014_09 |