HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Imidazo[1,2-a]pyridine-6-carbaldehyde → HCID 57917488, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Imidazo[1,2-a]pyridine-6-carbaldehyde | HCID 7164582 | — |
| Edukt | 5-Fluoroquinoline-6-carbaldehyde | HCID 57917315 | — |
| Edukt | 3-Bromo-6-(1-methyl-1h-pyrazol-4-yl)-imidazo[1,2-b]pyridazine | HCID 68632486 | — |
| Produkt | HCID 57917488 | HCID 57917488 | — |
Reaktionsschritte
(rac)-(5-Fluoro-quinolin-6-yl)-[6-(1-methyl-1H-pyrazol-4-yl)-imidazo[1,2-b]pyridazin-3-yl]-methanol was obtained analogously to Stage 9.1 by replacing 3-bromo-6-chloro-imidazo[1,2-b]pyridazine with 3-bromo-6-(1-methyl-1h-pyrazol-4-yl)-imidazo[1,2-b]pyridazine (Stage 8.1) and imidazo[1,2-a]pyridine-6-carbaldehyde with 5-fluoro-quinoline-6-carbaldehyde (Intermediate A) (tR 0.90 min (conditions 1), (MH+=375).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08822468B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-439889cdcf884be28c6710a5346c474e |
| Quellennotiz | uspto-grants-2014_09 |