4-Amino-M-cresol hydrochloride → 1-(4-Hydroxy-2-methylphenyl)-6-methyl-2,3-dihydropyrrolo-[3,2-c]cinnoline hydrochloride

Beteiligte Stoffe

Reaktionsschritte

3-(2-Chloroethyl)-4-chloro-8-methylcinnoline (2 g, 0.0083 mol) and 4-hydroxy-2-methylaniline hydrochloride (1.32 g, 0.0083 mol) in isopropanol (50 ml) were heated under reflux in a nitrogen atmosphere for 20 hours. The solid obtained was collected by filtration and dried. Recrystallization from isopropanol/ethanolic HCl gave the title compound as a partial hydrate, 0.64 g, m.p. 292-294°.

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