HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(4-Methyl-1-piperazine)propan-1-ol → n-[(5s)-3-(3-(4-Methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5h-dibenzo[a,c]cyclohepten-5-yl]acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(4-Methyl-1-piperazine)propan-1-ol | HCID 79208 | — |
| Edukt | N-Acetylcolchicinol | HCID 97865 | — |
| Produkt | n-[(5s)-3-(3-(4-Methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5h-dibenzo[a,c]cyclohepten-5-yl]acetamide | HCID 9848717 | 22% |
Reaktionsschritte
Using an analogous procedure to that described for Example 7, N-acetyl-colchicinol was reacted with 4-(3-hydroxypropyl)-1-methylpiperazine to give N-[(5S)-3-(3-(4-methylpiperazin-1-yl)propoxy)-9,10,11-trimethoxy-6,7-dihydro-5H-dibenzo[a,c]cyclohepten-5-yl]acetamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07135502B1 |
| Quelldatensatz | uspto-grants-2006_11 |
| ORD ID | ord-6dd86504269c4126a9a6f0039fa5a4eb |
| Quellennotiz | uspto-grants-2006_11 |