HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Acetic Anhydride → 2-Pyridinemethanol, 2-acetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Acetic Anhydride | HCID 7918 | — |
| Edukt | 2-Methylpyridine 1-oxide | HCID 13602 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | 2-Pyridinemethanol, 2-acetate | HCID 13881 | — |
Reaktionsschritte
A solution of the 2-methyl pyridine N-oxide (1.0 mmol) in acetic anhydride (5 mmol) was heated to reflux for 0.5 h. Work-up (EtOAc), drying (MgSO4), evaporation and purification by preparative TLC or flash chromatography afforded the 2-(acetoxymethyl)pyridine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07138401B2 |
| Quelldatensatz | uspto-grants-2006_11 |
| ORD ID | ord-46b932fbdc8540ac87584522c6800eb6 |
| Quellennotiz | uspto-grants-2006_11 |