HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Phosphorodichloridic acid, phenyl ester → Ethyl 4-chloro-1-{[4-(methyloxy)phenyl]methyl}-1H-pyrrolo[3,2-c]pyridine-7-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Phosphorodichloridic acid, phenyl ester | HCID 13038 | — |
| Edukt | Ethyl 1-{[4-(methyloxy)phenyl]methyl}-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carboxylate | HCID 57840819 | — |
| Produkt | Ethyl 4-chloro-1-{[4-(methyloxy)phenyl]methyl}-1H-pyrrolo[3,2-c]pyridine-7-carboxylate | HCID 57840887 | — |
Reaktionsschritte
Prepared in a similar manner to Example 243(e) using ethyl 1-{[4-(methyloxy)phenyl]methyl}-4-oxo-4,5-dihydro-1H-pyrrolo[3,2-c]pyridine-7-carboxylate (14.45 g) and phenyl dichlorophosphate (100 ml) to afford the title compound as a yellow oil (7.2 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07589206B2 |
| Quelldatensatz | uspto-grants-2009_09 |
| ORD ID | ord-e85f43810b5b43549820003a70ed2893 |
| Quellennotiz | uspto-grants-2009_09 |