HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
methyl (4-amino-2,3-dihydro-1H-indol-3-yl)acetate → 1,2,2a,5-Tetrahydropyrrolo[4,3,2-de]quinolin-4(3H)-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | methyl (4-amino-2,3-dihydro-1H-indol-3-yl)acetate | HCID 10104433 | — |
| Lösungsmittel | O-Xylene | HCID 7237 | — |
| Produkt | 1,2,2a,5-Tetrahydropyrrolo[4,3,2-de]quinolin-4(3H)-one | HCID 10442192 | — |
Reaktionsschritte
1.80 g (8.73 mmol) methyl (4-amino-2,3-dihydro-1H-indol-3-yl)acetate in 100 mL xylene were refluxed for 30 h. The reaction mixture was evaporated down and purified by flash chromatography. The product-containing fractions were combined and evaporated down.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08829006B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-cdbb45a4f8dd41cead89feda40477465 |
| Quellennotiz | uspto-grants-2014_09 |