Thionyl Chloride → 4-Benzyloxy-1-methyl-1H-indole-2-carbonyl chloride

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

To a stirred suspension of 4-benzyloxy-1-methyl-1H-indole-2-carboxylic acid (0.75 g) in benzene (5 mL) was added thionyl chloride (2.8 mL) in benzene (5 mL) followed by heated at 80° C. for 45 min. to give a clear orange solution. Evaporation to dryness gave 0.80 g of the title compound as an orange solid, which was used without further purification.

Herkunft & Nachweise