Hydroquinone → 2-(Benzothiazol-6-ylaminomethyl)-3,3,3-trifluoro-propionic Acid

Beteiligte Stoffe

Reaktionsschritte

Benzothiazol-6-ylamine (1 g, 6.66 mmol) was reacted with 2-trifluoromethyl-acrylic acid (1.39 g, 9.99 mmol), benzene-1,4-diol (51.3 mg, 0.46 mmol) and toluene (10 mL) to afford the crude product. Purification by column chromatography on silica gel (30% ethyl acetate in hexane) afforded 380 mg of the product (19.67% yield).

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