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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 8067Erstellt: 24. Oktober 2026

Pyridine → 1-benzyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester

https://huagongshe.com/de/reaction/8067

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktPyridineHCID 1049—
EduktEthyl 2-acetylacetoacetateHCID 79063—
EduktBenzylhydrazine dihydrochlorideHCID 146540—
LösungsmittelEthanolHCID 702—
Produkt1-benzyl-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl esterHCID 9943096—

Reaktionsschritte

Similar to Example 1, equimolar amounts of benzylhydrazine dihydrochloride and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of 50% pyridine in ethanol. The resulting oil was determined to be the named product by 1H-NMR (CDCl3, ppm): 1.35 t (3H); 2.44 s (3H); 2.45 s (3H); 4.38 a (2H); 5.25 s (2H); 7.08 d (2H); 7.29 m (3H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07087634B2
Quelldatensatzuspto-grants-2006_08
ORD IDord-cdce1d85350340c0aefc14ad614d2d49
Quellennotizuspto-grants-2006_08