HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methylamine tetrahydrofuran → 6-({5-[2-(ethylamino)ethoxy]pyridin-2-yl}oxy)-N-(5-methylpyrazin-2-yl)quinazoline-4-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methylamine tetrahydrofuran | HCID 66615946 | — |
| Edukt | 5-(2,2-Diethoxyethoxy)-2-fluoropyridine | HCID 68429706 | — |
| Edukt | 4-((5-Methylpyrazin-2-yl)amino)quinazolin-6-ol | HCID 135618222 | — |
| Produkt | 6-({5-[2-(ethylamino)ethoxy]pyridin-2-yl}oxy)-N-(5-methylpyrazin-2-yl)quinazoline-4-amine | HCID 59508829 | — |
Reaktionsschritte
Using 4-[(5-methylpyrazin-2-yl)amino]quinazolin-6-ol, 5-(2,2-diethoxyethoxy)-2-fluoropyridine and 2 Methylamine/tetrahydrofuran solution, and in the same manner as in Example 31 or according to a method similar to it or according to a combination thereof with an ordinary method, the entitled compound (52 mg) was obtained as a pale yellow amorphous solid.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08846700B2 |
| Quelldatensatz | uspto-grants-2014_09 |
| ORD ID | ord-2023a86ea0534b57a7e4088f55c86661 |
| Quellennotiz | uspto-grants-2014_09 |