HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chloro-alpha-(3-methoxyphenyl)-3-pyridinemethanol → (2-Chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Chloro-alpha-(3-methoxyphenyl)-3-pyridinemethanol | HCID 20145733 | — |
| Katalysator | HCID 178418406 | HCID 178418406 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | (2-Chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanone | HCID 10243711 | 66% |
Reaktionsschritte
Combine (2-chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanol (9.40 g, 37.6 mmol), manganese (IV) oxide (30.0 g, 0.345 mol) and toluene (500 mL) and heat to reflux for one hour. Filter reaction mixture through celite, wash with toluene:dichloromethane mixture and evaporate to give the title compound (1.63 g, 66% Yield).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07253165B2 |
| Quelldatensatz | uspto-grants-2007_08 |
| ORD ID | ord-c911483f263244228b471f1f0eb54e62 |
| Quellennotiz | uspto-grants-2007_08 |