Trimethylsilyl cyanide → alpha-(4-Difluoromethoxyphenyl)-alpha-(4-methylthioanilino)acetonitrile

Beteiligte Stoffe

Reaktionsschritte

Following a procedure similar to that described in Example 1(i), but using 4-difluoromethoxybenzaldehyde and 4-methylthioaniline as starting materials, N-(4-difluoromethoxybenzylidene)-4-methylthioaniline was obtained in a yield of 91%. This aniline compound and trimethylsilyl cyanide were then reacted together in a similar manner to that described in Example 1(ii), to give the title compound as a slightly yellow powder (yield 80%).

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