HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methylamine → 2-(4-Bromo-phenyl)-N-methyl-isobutyramide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methylamine | HCID 6329 | — |
| Edukt | Monoethyl malonate | HCID 70615 | — |
| Edukt | (R)-4-bromo-alpha-methylbenzylamine | HCID 853000 | — |
| Edukt | 2-(4-Bromophenyl)-2-methylpropanoic acid | HCID 10933679 | — |
| Produkt | 2-(4-Bromo-phenyl)-N-methyl-isobutyramide | HCID 58762757 | 84% |
Reaktionsschritte
The title compound was prepared as described in Step 1 of Example A(39), where 2-(4-bromophenyl)-2-methyl propionic acid was substituted for ethyl hydrogen malonate and methyl amine was substituted instead of (R)-(+)-1-(4-bromophenyl)ethylamine on that example. Yield 84%.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07148226B2 |
| Quelldatensatz | uspto-grants-2006_12 |
| ORD ID | ord-a025f88052e6471dbade514643702c64 |
| Quellennotiz | uspto-grants-2006_12 |