HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isobutylamine → 4-Isobutyl-3-nitro quinoline
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isobutylamine | HCID 6558 | — |
| Edukt | Triethylamine | HCID 8471 | — |
| Edukt | 4-Chloro-3-nitroquinoline | HCID 11275808 | — |
| Lösungsmittel | Toluene | HCID 1140 | — |
| Produkt | 4-Isobutyl-3-nitro quinoline | HCID 22590498 | — |
Reaktionsschritte
4-chloro-3-nitro-quinoline is reacted with isobutyl amine in the presence of triethylamine (TEA) at between −10 and +15° C. in toluene, while excluding moisture. After washing and phase separation, the organic solution is ready for the next step.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07153967B2 |
| Quelldatensatz | uspto-grants-2006_12 |
| ORD ID | ord-2a09a96c7904400188fdc1d1d1d2e948 |
| Quellennotiz | uspto-grants-2006_12 |