Dimethylamine → 3-Dimethylamino-1,1-diphenyl-propan-2-ol

Beteiligte Stoffe

Reaktionsschritte

1,1-Diphenyl-3-bromopropan-2-ol (500mg.) prepared as described in Example 20 was treated with excess dimethylamine in ethanol and the solution allowed to stand overnight. Solvent was removed by evaporation and the residue dissolved in dilute hydrochloric acid and ether. Basification of the acid extract and isolation through ether in the usual manner gave 3-dimethylamino-1,1-diphenyl-propan-2-ol (330mg, 75%) m.p. 72° - 73°

Herkunft & Nachweise