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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 887239Erstellt: 24. Oktober 2026

Ammonia → N-[1-(4-bromophenyl)ethyl]-2-(5-isoquinolinyl)acetamide

https://huagongshe.com/de/reaction/887239

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktAmmoniaHCID 222—
Edukt4-BromobenzylamineHCID 77571—
Edukt1-(4-Bromophenyl)ethylamineHCID 91175—
EduktMethyl 2-(isoquinolin-5-yl)acetateHCID 22337565—
ProduktN-[1-(4-bromophenyl)ethyl]-2-(5-isoquinolinyl)acetamideHCID 22032664—

Reaktionsschritte

The title compound was prepared using the procedure described in Example 132C using the product from Example 133B and 1-(4-bromophenyl)ethanamine instead of the product from Example 132B and 4-bromobenzylamine. 1H NMR (300 MHz, d6-DMSO) 9.81 (s, 1H), 9.00 (d, 1H), 8.70 (d, 1H), 8.48 (d, 1H), 8.40 (d, 1H), 8.04 (d, 1H), 7.92 (m, 1H), 7.51 (d, 2H), 7.23 (d, 2H), 4.84 (m, 1H), 4.10 (s, 2H), 1.35 (d, 3H). MS (DCI/NH3) m/e 369 (M+H)+; Anal. Calcd. For C19H17N2OBr.1.0HCl.1.0H2O: C, 53.86; H, 4.76; N, 6.61. Found: C, 53.47; H, 4.53; N, 6.76.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08247413B2
Quelldatensatzuspto-grants-2012_08
ORD IDord-227772c128ec46019e6b2d03e945b27a
Quellennotizuspto-grants-2012_08