HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
L-(+)-Cysteine → Isopenicillin N
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | L-(+)-Cysteine | HCID 5862 | — |
| Edukt | L-Valine | HCID 6287 | — |
| Edukt | Penicillin G Potassium | HCID 23664709 | — |
| Produkt | Isopenicillin N | HCID 440723 | — |
Reaktionsschritte
The first two steps in the biosynthesis of penicillin in P. chrysogenum are the condensation of the three amino acids L-5-amino-5-carboxypentanoic acid (L-α-aminoadipic acid) (A), L-cysteine (C) and L-valine (V) into the tripeptide LLD-ACV, followed by cyclisation of this tripeptide to form isopenicillin N. This compound contains the typical β-lactam structure.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06995003B1 |
| Quelldatensatz | uspto-grants-2006_02 |
| ORD ID | ord-ca00ed0437834eb09d007cac56b83769 |
| Quellennotiz | uspto-grants-2006_02 |