HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrazine hydrate (1:1) → N-(1-(3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)ethyl)acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Edukt | Ethyl 3-acetamido-2-oxobutanoate | HCID 22245807 | — |
| Edukt | 2-(3,4-Dimethoxyphenyl)ethanimidamide hydrochloride | HCID 22245813 | — |
| Produkt | N-(1-(3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl)ethyl)acetamide | HCID 135697918 | — |
Reaktionsschritte
Analogously to Example 7A, 20.0 g (86.7 mmol) of 2-(3,4-dimethoxyphenyl)ethanamidine hydrochloride (Example 5A) are reacted with 5.21 g (104 mmol) of hydrazine hydrate and 24.3 g (130 mmol) of ethyl 3-(acetylamino)-2-oxobutanoate (Example 6A) to give N-{1-[3-(3,4-dimethoxybenzyl)-5-oxo-4,5-dihydro-1,2,4-triazin-6-yl]ethyl}acetamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06998402B2 |
| Quelldatensatz | uspto-grants-2006_02 |
| ORD ID | ord-4ee6ace81bc449eb9b4a983a9986615a |
| Quellennotiz | uspto-grants-2006_02 |