Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Acetic Acid | HCID 176 | — |
| Edukt | Water | HCID 962 | — |
| Edukt | 3-(4-Methoxyphenyl)prop-2-enenitrile | HCID 34240 | — |
| Katalysator | Nickel | HCID 935 | — |
| Lösungsmittel | Pyridine | HCID 1049 | — |
| Produkt | 3-(4-Methoxyphenyl)prop-2-enal | HCID 230995 | 35% |
Reaktionsschritte
To 2 g (12.6 mmol) 4-methoxycinnamonitrile in 10:10:20 ml H2O:HOAc:pyridine was added 5 g (47 mmol) NaH2PO2 (hypophosphite) followed by 2 g RaNi. After stirring 3 hours at 50° C., the reaction mixture was filtered, extracted with CH2Cl2, washed with dilute HCl, washed with H2O and evaporated to give 0.7 g (35% yield) 4-methoxycinnamaldehyde, a yellow solid, m.p. 47° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | USRE038761E1 |
|---|
| Quelldatensatz | uspto-grants-2005_07 |
|---|
| ORD ID | ord-69f1bb31c39f41839482b13f761928dd |
|---|
| Quellennotiz | uspto-grants-2005_07 |
|---|
