1-(6-Nitroindolin-1-yl)ethanone → 1-Acetyl-6-aminoindoline

Beteiligte Stoffe

Reaktionsschritte

1-Acetyl-6-nitroindoline (3.8 g, 18.3 mmol) was suspended in EtOAc (200 mL). Pd/C (650 mg, 10%) was added, and the mixture was hydrogenated at 40-55 p.si.i. for 2 hours. The mixture was then filtered through celite. The filtrate was concentrated, and the residue was triturated with ether to yield 1-acetyl-6-aminoindoline (3.18 g, 99%) as an orange solid.

Herkunft & Nachweise