Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Propanal | HCID 527 | — |
| Edukt | Piperidine | HCID 8082 | — |
| Edukt | 3,5-Dimethyl-4-nitroisoxazole | HCID 261410 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | HCID 66995125 | HCID 66995125 | 225% |
Reaktionsschritte
3,5-dimethyl-4-nitroisoxazole (2.50 g, 17.6 mmol) in 25 mL EtOH was dissolved. Piperidine (0.174 mL, 1.76 mmol) was added followed by propionaldehyde (1.52 mL, 21.1 mmol). The solution was heated at 90° C. overnight. The solution was concentrated and chromatographed using EtOAc to obtain the title compound (0.650 g, 22.5% yield).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US08022223B2 |
|---|
| Quelldatensatz | uspto-grants-2011_09 |
|---|
| ORD ID | ord-a9d4ad6753aa4fba9ae239735904992f |
|---|
| Quellennotiz | uspto-grants-2011_09 |
|---|
