HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 915670Erstellt: 24. Oktober 2026
2-Propynoic acid, 3-phenyl-, ethyl ester → Ethyl-4-phenyl-3-furoate
https://huagongshe.com/de/reaction/915670
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | 2-Propynoic acid, 3-phenyl-, ethyl ester | HCID 91516 | — |
| Edukt | 4-Phenyl-1,3-oxazole | HCID 589279 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | Ethyl-4-phenyl-3-furoate | HCID 15037153 | 78,4% |
Reaktionsschritte
Mix 4-Phenyl oxazole (3.33 g, 23.0 mmol) and ethyl phenylpropiolate (4.0 g, 23.0 mmol) in a sealed tube and heat at 220° C. for 20 hours. Perform flash-chromatography on silica gel eluting with 4:1 Hex/ethyl acetate to afford 3.9 g of 4-phenylfuran-3-carboxylic acid ethyl ester as a yellow oil. MS: m/e=217 (MH+).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patentnummer | US07265246B2 |
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| Quelldatensatz | uspto-grants-2007_09 |
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| ORD ID | ord-9fd118029536481387b3a1242356d996 |
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| Quellennotiz | uspto-grants-2007_09 |
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