HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Methylmorpholine → N-(7-Methoxy-4-phenyl-thiazolo[5,4-c]pyridin-2-yl)-2-morpholin-4-yl-isonicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Methylmorpholine | HCID 7972 | — |
| Edukt | 2-(Morpholin-4-yl)isonicotinic acid | HCID 2762479 | — |
| Edukt | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Edukt | 7-Methoxy-4-phenyl-thiazolo[5,4-c]pyridin-2-ylamine | HCID 86038474 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | N-(7-Methoxy-4-phenyl-thiazolo[5,4-c]pyridin-2-yl)-2-morpholin-4-yl-isonicotinamide | HCID 11510622 | — |
Reaktionsschritte
From 2-(4-morpholinyl)-4-pyridinecarboxylic acid, HATU and N-methylmorpholine in THF, then treatment with 7-methoxy-4-phenyl-thiazolo[5,4-c]pyridin-2-ylamine. ES-MS m/e (%): 448 (M+H+, 100).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07273865B2 |
| Quelldatensatz | uspto-grants-2007_09 |
| ORD ID | ord-f91af5cebcf74b3c97a4e3abbf8dcb31 |
| Quellennotiz | uspto-grants-2007_09 |