HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Potassium Carbonate → 2-(2,4,6-Triiodophenoxy)nonane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | 2,4,6-Triiodophenol | HCID 11862 | — |
| Edukt | 2-Methanesulfonyloxynonane | HCID 14916006 | — |
| Edukt | 2-(2,4,6-Triiodophenoxy)pentadecane | HCID 15343309 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 2-(2,4,6-Triiodophenoxy)nonane | HCID 15343313 | 68% |
Reaktionsschritte
The 2-methanesulfonyloxynonane (22.8 g, 102 mmol), triiodophenol (48.8 g, 103 mmol) and potassium carbonate (14.2 g, 103 mmol) were reacted in DMF (206 ml) as per 2-(2,4,6-triiodophenoxy)pentadecane except at an oil bath temperature of 82° C. for 14 hrs. The reaction was processed as for 2-(2,4,6-triiodophenoxy)pentadecane to provide a light brown oil. Flash column chromatography (silica, hexanes) provided 2-(2,4,6-triiodophenoxy)nonane (40.8 g, 68.0%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05607660 |
| Quelldatensatz | uspto-grants-1997_03 |
| ORD ID | ord-5924d4a5d885450cb80faddba131a647 |
| Quellennotiz | uspto-grants-1997_03 |