HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
tert-Butyl piperazine-1-carboxylate → 2-cyclopropylmethyl-4-[3-(4-tert-butoxycarbonyl-1-piperazinyl)propyl]-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Edukt | 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(3-metha nesulfonyloxypropyl)-2H-pyridazin-3-one | HCID 21991559 | — |
| Produkt | 2-cyclopropylmethyl-4-[3-(4-tert-butoxycarbonyl-1-piperazinyl)propyl]-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one | HCID 21991398 | 76,9% |
Reaktionsschritte
Following the procedure of Example 1(10), 2-cyclopropylmethyl-6-(3-fluoro-4-methoxyphenyl)-4-(3-methanesulfonyloxypropyl)-2H-pyridazin-3-one and tert-butyl 1-piperazinecarboxylate were reacted to yield the title compound as a yellow oil (yield: 76.9%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06869954B2 |
| Quelldatensatz | uspto-grants-2005_03 |
| ORD ID | ord-cf7e16d1c0fb40da977b04f1495b90ae |
| Quellennotiz | uspto-grants-2005_03 |