N-Methylaniline → 6-Methoxy-pyridazine-3-sulfonic acid methyl-phenyl-amide

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

A mixture was prepared of 6-methoxy-pyridazine-3-sulfonyl fluoride from Example 11 (1.62 mmol, 312 mg) and N-methyl aniline (24.3 mmol, 0.26 mL) and heated at 100° C. for 12 hours. The mixture was then cooled. The resulting solid residue was purified by silica gel chromatography to isolate the title compound (53%, 240 mg); M+, 279.

Herkunft & Nachweise