4-(4-Aminophenyl)morpholin-3-one

HCID 11194854CAS 438056-69-0
Substructure searchFind similar structures

Basic information

Standard SMILES
Nc1ccc(N2CCOCC2=O)cc1
InChIKey
MHCRLDZZHOVFEE-UHFFFAOYSA-N
Molecular formula
C10H12N2O2
Average molar mass
192.21 g/mol
Monoisotopic mass
192.08987762

Names & identifiers

Preferred name
4-(4-Aminophenyl)morpholin-3-one
IUPAC
4-(4-aminophenyl)morpholin-3-one
English name
4-(4-AMINOPHENYL)MORPHOLIN-3-ONE
Molecular formula
C10H12N2O2
Molecular weight
192.21

Names & synonyms

4-(4-aminophenyl)morpholin-3-one438056-69-0DTXSID90458314RefChem:513837DTXCID80409133610-147-84-(4-aminophenyl)-3-Morpholinone3-Morpholinone, 4-(4-aminophenyl)-MFCD08236742C10H12N2O2Rivaroxaban Impurity 64H6N2PY6WST
Show more names
Rivaroxaban InterMediate4-(4-AMINO PHENYL)MORPHOLINE-3-ONE4-(4-aMinophenyl)Morpholine-3- ketonein-3-one2-Amino-11-picoline4-(4-aminophenyl)morRivaroxaban Impurity 37Rivaroxaban intermdiateAminophenylmorpholinone
4-(3-Oxomorpholino)aniline4-(3-OXO-4-MORPHOLINYL)ANILINE4-(4-Morpholin-3-onyl)anilineN-(4-Aminophenyl)-3-morpholinone4-(4-aminophenyl) morpholin-3-oneAKOS006284751AC-2721HE-0208

Database identifiers

CAS
438056-69-0
PubChem CID
11194854
DTXSID
DTXSID90458314
UNII
H6N2PY6WST
EC Number
610-147-8
Nikkaji
J2.551.238C

Properties

Computed structural properties

XLogP
0.3
Topological polar surface area
55.6 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
3
Rotatable bonds
1
Heavy atoms
14

Physicochemical properties

Melting point
171 to · 171.0 to 175.0 °C
Boiling point
502.3 · 502.3±45.0 °C(Predicted)
Density
1.268 · 1.268
vapor pressure
0 Pa · 0Pa at 25℃
storage temp.
Keep in dark place,Inert atmosphere,Room temperature
solubility
DMSO (Slightly), Methanol (Slightly, Heated)

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H315 (24%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 25 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory InformationStatus: Cease Manufacture Update: 06-02-2013 https://echa.europa.eu/registration-dossier/-/registered-dossier/6284
Hazard Classes and CategoriesSkin Irrit. 2 (24%)

Safety data

wgk
WGK 3
hs_code
29349990
Signal word
Warning
Symbol(GHS)
GHS07
safety_code
24/25
hazard_class
IRRITANT

Chemistry & industry

Applications

Uses4-(4-AMINOPHENYL)MORPHOLIN-3-ONE is used in the preparation of various Morpholine based pharmaceuticals.

UsesRivaroxaban intermediate

Upstream & downstream products

Suppliers50 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
上海同昌生物医药科技有限公司+86-21-33282107

Related reactions

82 records
New reaction record

Linked notes

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4-(4-Aminophenyl)morpholin-3-one (HCID 11194854)｜Huagongshe