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Basic information
- Standard SMILES
NC(N)=NCCC[C@H](N)C(=O)O.O=C(O)CCC(=O)C(=O)O- InChIKey
PGRNZHOQVAPMFX-WCCKRBBISA-N- Molecular formula
- C11H20N4O7
- Average molar mass
- 320.302 g/mol
- Monoisotopic mass
- 320.13319898
Names & identifiers
- Preferred name
- 2-Oxopentanedioic acid - L-arginine (1:1)
- IUPAC
- 2-Oxopentanedioic acid--L-arginine (1/1)
- English name
- L-Arginine alpha-ketoglutarate
- Molecular formula
- C11H20N4O7
- Molecular weight
- 320.3
Names & synonyms
Database identifiers
- CAS
16856-18-1、5256-76-8- PubChem CID
- 11427178
- DTXSID
DTXSID60937505- UNII
- TVJ23A89RU
- EC Number
- 240-882-6
Properties
Physicochemical properties
- storage temp.
- 2 · 2-8°C
- InChI
- InChI=1/C6H14N4O2.C5H6O5/c7-4(5(11)12)2-1-3-10-6(8)9;6-3(5(9)10)1-2-4(7)8/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1-2H2,(H,7,8)(H,9,10)/t4-;/s3
- InChIKey
- PGRNZHOQVAPMFX-NDILARRWNA-N
- SMILES
- C([C@H](N)C(=O)O)CCNC(N)=N.C(=O)(C(=O)O)CCC(=O)O |&1:1,r|
- CAS DataBase Reference
- 16856 · 16856-18-1(CAS DataBase Reference)
- FDA UNII
- 23 A89RU · TVJ23A89RU
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
Safety & regulation
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
DescriptionL-arginine α-ketoglutarate (L-Arginine alpha-ketoglutarate) is a unique amino acid derivative, constituted by a combination of two L-arginine molecules and one 2-oxoglutarate molecule. This compound has attracted considerable interest in the past few years because of its potential use in various scientific research applications and its noteworthy biochemical and physiological effects. L-arginine α-ketoglutarate has showcased versatility in research, serving as an enzyme reaction substrate, a stabilizing agent for proteins and enzymes, and an antioxidant. It has also been employed in studies that examine the impact of various substances and potential toxins on the human body. While the exact mechanism of action of L-Arginine α-ketoglutarate is yet to be fully deciphered, it is speculated that it plays a role in the manufacture of nitric oxide, a significant signaling molecule involved in numerous physiological processes. Furthermore, L-Arginine α-ketoglutarate is believed to participate in the regulation of both cellular metabolism and gene expression.
UsesL-arginine alpha-ketoglutarate is a natural product. It has been shown to enhance the release of NO in the body. It is suggested that muscular performance be facilitated by increasing blood flow and oxygen and nutrient delivery to the working muscle[1-2].
Uses[1] Wax, B. et al. “Effect of L-Arginine Alpha-Ketoglutarate Ingestion on Muscular Strength and Endurance.” 2011. 0.[2] Benjamin Wax. “Acute L-arginine alpha ketoglutarate supplementation fails to improve muscular performance in resistance trained and untrained men.” Journal of the International Society of Sports Nutrition 9 1 (2012): 17.
Upstream & downstream products
Upstream raw materials
Suppliers50 total
Related reactions
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