Identifiers & Physical Properties
| CAS No. | 14221-01-3 |
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| Molecular formula | C72H60P4Pd |
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| Average molar mass | 1,155.6 g/mol |
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| SMILES | [Pd].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1 |
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| InChIKey | NFHFRUOZVGFOOS-UHFFFAOYSA-N |
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| PubChem CID | 11979704 |
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| EC No. | 238-086-9 |
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| DTXSID | DTXSID9065732 |
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Chemical & Physical Properties
| Topological polar surface area | 0 |
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| Hydrogen bond donors | 0 |
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| Hydrogen bond acceptors | 0 |
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| Rotatable bonds | 12 |
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| Heavy atoms | 77 |
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| Formal charge | 0 |
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| Complexity | 202 |
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| Chemical classes | Metals -> Organic Compounds, Metal Salts |
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| Physical Description | Crystals[Sigma-Aldrich MSDS] |
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Safety & Regulations
| GHS classification | This chemical does not meet GHS hazard criteria for 0.5% (1 of 193) of reports.WarningH302 (83.9%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P270, P272, P273, P280, P301+P317, P302+P352, P321, P330, P333+P317, P362+P364, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 193 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
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| Regulatory information | Chemical: Palladium, tetrakis(triphenylphosphine)-, (T-4)-Status: Cease Manufacture Update: 18-11-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/19027Palladium, tetrakis(triphenylphosphine)-, (T-4)-: Does not have an individual approval but may be used under an appropriate group standard |
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| Other safety information | IMAP assessments - Palladium, tetrakis(triphenylphosphine)-, (T-4)-: Environment tier I assessment |
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| Hazards summary | May cause irritation[Sigma-Aldrich MSDS] See Palladium. See Triphenylphosphine. |
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| Hazard Classes and Categories | Acute Tox. 4 (83.9%) |
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| Health effects | Contact with palladium may cause palladium sensitivity and allergy. Animal studies have shown that palladium may damage the liver and kidney. (L798) |
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| Toxicity summary | Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, and interact with functional groups of macromolecules, such as proteins or DNA. Palladium complexes binding to DNA and RNA leads to strand breakage. Palladium ions are able to inhibit most major cellular functions, including DNA and RNA synthesis. Palladium compounds have been shown to bind to and inhibit various enzymes, including creatine kinase and prolyl hydroxylase. (L798) |
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| Signs and Symptoms | Skin contact with palladium may cause contact dermatitis, erythema, and oedema. (L798) |
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| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
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