HuagongsheHuagongshe Chemistry Print Report · For research reference only
Norfloxacin hydrochloride
NorfloxacineHCl · Norfloxacinehydrochloride · Hydrochloric acid and norfloxacin · Norfloxacin hydrochloride (MK-0366) · Norfloxacinehydrochloride USP/EP/BP · 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazin-1-yl-quinolin-3-carboxylic acid HCl · 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-Quinolinecarboxylic acid hydrochloride (1:1) · 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-, hydrochloride (1:1)
Identifiers & Physical Properties
| CAS No. | 104142-93-0 |
|---|---|
| Molecular formula | C16H19ClFN3O3 |
| Average molar mass | 355.79 g/mol |
| SMILES | CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21.Cl |
| InChIKey | JJWDELPVPRCLQN-UHFFFAOYSA-N |
| PubChem CID | 12733888 |
| ChEMBL | CHEMBL4635810 |
Chemical & Physical Properties
| Topological polar surface area | 72.9 |
|---|---|
| Hydrogen bond donors | 3 |
| Hydrogen bond acceptors | 7 |
| Rotatable bonds | 3 |
| Heavy atoms | 24 |
| Formal charge | 0 |
| Complexity | 519 |
| Melting point | >300 °C |
| Storage conditions | Store at -20°C |
| Solubility | Soluble in DMSO |
| Physical state | Powder |
| FDA UNII | 7O3ULA741Z |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H302-H315-H319-H335 |
| GHS precautionary statements | P280-P305+P351+P338 |
| Hazard symbols | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Safety & Regulations
| Risk statements (R) | 11-34 |
|---|---|
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | F,C |
| Safety statements (S) | 16-26-36/37/39-45 |
| GHS hazard statements | H302-H315-H319-H335 |
| GHS precautionary statements | P280-P305+P351+P338 |
Applications & Uses
Uses
Norfloxacin hydrochloride (MK-0366 hydrochloride) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria, which functions by inhibiting DNA gyrase.