2-Methyl-4-amino-6-hydroxypyrimidine

HCID 135431330CAS 767-16-8

Basic information

Standard SMILES
Cc1nc(N)cc(=O)[nH]1
InChIKey
MVHONLHZERWNRF-UHFFFAOYSA-N
Molecular formula
C5H7N3O
Average molar mass
125.13 g/mol
Monoisotopic mass
125.05891186

Names & identifiers

Preferred name
2-Methyl-4-amino-6-hydroxypyrimidine
IUPAC
4-amino-2-methyl-1H-pyrimidin-6-one
English name
4-Amino-6-hydroxy-2-methylpyrimidine
Molecular formula
C5H7N3O
Molecular weight
125.13

Names & synonyms

4-Amino-6-hydroxy-2-methylpyrimidine6-Amino-2-methyl-4(1H)-pyrimidinone6-Amino-2-methyl-1H-pyrimidin-4-one4(1H)-Pyrimidinone, 6-amino-2-methyl-4(3H)-Pyrimidinone, 6-amino-2-methyl-L9V7LC4LHZ4-Amino-6-oxo-2-methylpyrimidine4-Pyrimidinol, 6-amino-2-methyl-NSC 26362EINECS 212-182-0NSC-263622-Methyl-4-amino-6-hydroxypyrimidine
Show more names
AKOS BBS-000021326-Amino-2-Methyl-42-Methyl-4-aminopyrimidin-6-ol6-AMINO-2-METHYL-4-PYRIMIDINOL6-amino-2-methyl-4(1h)-pyrimidinon6-AMINO-2-METHYL-3H-PYRIMIDIN-4-ONE
NSC 171558NSC-171558DTXSID6061107RefChem:475568DTXCID40479134-Pyrimidinol, 6-amino-2-methyl-(8CI)767-16-86-amino-2-methylpyrimidin-4-ol

Database identifiers

CAS
767-16-8
PubChem CID
135431330
DTXSID
DTXSID6061107
UNII
L9V7LC4LHZ
EC Number
212-182-0
Nikkaji
J58.048A

Properties

Computed structural properties

XLogP
-1.2
Topological polar surface area
67.5 Ų
Hydrogen bond donors
2
Hydrogen bond acceptors
3
Rotatable bonds
0
Heavy atoms
9

Physicochemical properties

Melting point
300 °C · >300°C
Boiling point
228.1 · 228.1±43.0 °C(Predicted)
Density
1.44 · 1.44±0.1 g/cm3(Predicted)
storage temp.
Keep in dark place,Sealed in dry,Room Temperature
pka
10.45 · 10.45±0.50(Predicted)
CAS DataBase Reference
767 · 767-16-8(CAS DataBase Reference)

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 2.4% (1 of 41) of reports.

Danger

H302 (92.7%): Harmful if swallowed [Warning Acute toxicity, oral];H315 (95.1%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (92.7%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H335 (95.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 41 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Reported as not meeting GHS hazard criteria per 1 of 41 reports by companies.;There are 3 notifications provided by 40 of 41 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Hazard Classes and CategoriesAcute Tox. 4 (92.7%);Skin Irrit. 2 (95.1%);Eye Dam. 1 (92.7%);STOT SE 3 (95.1%)

Safety data

tsca
TSCA listed
Signal word
Warning
Symbol(GHS)
GHS07
safety_code
22-24/25
hazard_class
IRRITANT
Hazard statements
H317-H319

Chemistry & industry

Uses & manufacturing

General Manufacturing Information4(3H)-Pyrimidinone, 6-amino-2-methyl-: INACTIVE

Applications

Uses4-Amino-6-hydroxy-2-methylpyrimidine is a heterocyclic compound that can be used as an organic intermediate.

Suppliers36 total

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Suzhou Victorypharm Co.,Ltd.+86-13916956214 · [email protected]
环生美森医药技术(山东)有限公司0531-88762217 18301471076 · [email protected]
爱斯特(成都)生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

Related reactions

1 records

Linked notes

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