Basic information
- Standard SMILES
C- InChIKey
VNWKTOKETHGBQD-UHFFFAOYSA-N- Molecular formula
- C3H7O*
- Average molar mass
- 59.0871 g/mol
Names & identifiers
- Preferred name
- Hydroxypropyl cellulose
- English name
- Hydroxypropyl cellulose
- Molecular formula
- C3H7O*
- Molecular weight
- 59.08708
Names & synonyms
Database identifiers
- CAS
9004-64-2
Properties
Physicochemical properties
- Melting point
- 371.06 °C · 371.06 °C
- Density
- 0.5 g/mL · 0.5 g/mL at 25 °C (lit.)
- refractive index
- 1.56 · 1.5600
- storage temp.
- Room Temperature
- solubility
- polar oganic solvents: soluble
- form
- powder
- color
- White to light cream
- PH Range
- 5 · 5.0 - 8.5
- PH
- pH (20g/l, 25℃) : 5.0~7.5
- Odor
- 100 % · at 100.00%. odorless
- Viscosity
- 3 to · 3.0 to 6.0 mPa-s (2 %, H2O, 20℃)
- Water Solubility
- Soluble in polar organic solvents, in water at room temperature.Soluble in water, methyl alcohol, ethyl alcohol and other organic solvents.
- Merck
- 14 · 14,4841
- Stability
- Stable. Incompatible with strong oxidizing agents. Combustible.
- Cosmetics Ingredients Functions
- BINDINGVISCOSITY CONTROLLINGSURFACTANT - EMULSIFYINGFILM FORMINGEMULSION STABILISING
- Cosmetic Ingredient Review (CIR)
- Hydroxypropyl cellulose (9004-64-2)
- InChI
- InChI=1S/CH4/h1H4
- InChIKey
- VNWKTOKETHGBQD-UHFFFAOYSA-N
- SMILES
- C
- CAS DataBase Reference
- 9004 · 9004-64-2
- Substances Added to Food (formerly EAFUS)
- HYDROXYPROPYL CELLULOSE
- FDA 21 CFR
- 177.12 · 177.1200
- EWG's Food Scores
- 1 · 1
- FDA UNII
- HYDROXYPROPYL CELLULOSE (160000 WAMW) (0A7M0N7SPE)HYDROXYPROPYL CELLULOSE (650000 WAMW) (1L0RPI3ASP)LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE, UNSPECIFIED (2165RE0K14)HYDROXYPROPYL CELLULOSE (110000 WAMW) (5Y0974F5PW)LOW-SUBSTITUTED HYDROXYPROPYL CELLULOSE (11% HYDROXYPROPYL; 140000 MW) (599BTP6K9F)
- EPA Substance Registry System
- 2 · Cellulose, 2-hydroxypropyl ether (9004-64-2)
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 24 · NA.24
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H335-H332-H319-H315
- Precautionary statements
- 261 · P261-P271-P304+P340-P312-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- Safety Statements
- 24 · 24/25
- WGK Germany
- 1 · 1
- RTECS
- 9050000 · NF9050000
- F
- 3 · 3-10
- Autoignition Temperature
- 752 °F · 752 °F
- TSCA
- TSCA listed
- HS Code
- 39129000 · 39129000
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety data
- F
- 3-10
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 1
- tsca
- TSCA listed
- rtecs
- NF9050000
- hs_code
- 39129000
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 24/25
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H335-H332-H319-H315
- Autoignition Temperature
- 752 °F
- Precautionary statements
- P261-P271-P304+P340-P312-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362
Chemistry & industry
Applications
DescriptionHydroxypropyl cellulose (HPC) is a derivative of cellulose being soluble in both water and organic acid. It is excellent in trapping water and preventing water loss. It can be used to treat diseases associated with insufficient tear production such as keratoconjunctivitis sicca, recurrent corneal erosions, decreased corneal sensitivity, and exposure and neuroparalytic keratitis. It is also used as a lubricant of artificial eyes. It can also be used as a thickener, an emulsion stabilizer and binder. Moreover, it can be used as a sieving matrix for DNA separation through capillary and microchip electrophoresis. It is also the major ingredient of Cellugel, which is used in book conservation.
DescriptionHydroxypropyl cellulose is a cellulose ether containing hydroxypropyl substitution. It occurs as a white powder. It is soluble in water and in certain organic solvents. It may contain a suitable anticaking agent.
UsesHydroxypropyl Cellulose is used in the synthesis of nanoparticle carriers for drug delivery.
UsesAs emulsifier, stabilizer, whipping aid, protective colloid, film former or thickener in foods; as binder in ceramics and glazes; in hair and cosmetic Preparations; in vacuum-formed containers and blow-molded bottles; as suspending agent in PVC polymerization. Pharmaceutic aid (tablet coating agent).
UsesHydroxypropyl Cellulose is a gum that is nonionic water-soluble cellulose, obtained from the reaction of alkali cellulose with propyl- ene oxide at high temperatures and pressures. it is soluble in water below 40°c, is precipitated as a floc between 40°c and 45°c, and is insoluble above 45°c. the precipitation is reversible with the origi- nal viscosity being restored upon cooling below 40°c and stirring. it is used in whipped toppings as a stabilizing and foaming aid; in edible food coatings as a glaze and oil/oxygen barrier; and in fabri- cated foods as a binder. typical usage level is 0.05–1.0%.
General DescriptionHydroxypropyl cellulose (HPC) is biocompatible in nature and exhibits low critical solution temperature (LCST). It has been reported to be prepared by reacting cellulose with alkali, producing alkali cellulose which is consecutively reacted with propylene oxide. HPC is soluble in water at lower than RT. Viscosity behaves inversely to rise in temperature.
Upstream & downstream products
Upstream raw materials
Suppliers50 total
Additional notes
DefinitionA cellulose ether with hydroxypropyl substitution.
Related reactions
No reaction records under the current filter.
Linked notes
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