Hydroxypropyl cellulose

HCID 178587305CAS 9004-64-2

Basic information

Standard SMILES
C
InChIKey
VNWKTOKETHGBQD-UHFFFAOYSA-N
Molecular formula
C3H7O*
Average molar mass
59.0871 g/mol

Names & identifiers

Preferred name
Hydroxypropyl cellulose
English name
Hydroxypropyl cellulose
Molecular formula
C3H7O*
Molecular weight
59.08708

Names & synonyms

HPChydroxypropylL-HPCKLUCELLow-Substituted Hydroxypropyl celluloseHyproloseIFFHydroxylpropyl celluloseHYDROXYPROPYLCELLULOSE, M.W.60,000Hydroxypropyl cellulose - Average MW 80,000

Database identifiers

CAS
9004-64-2

Properties

Physicochemical properties

Melting point
371.06 °C · 371.06 °C
Density
0.5 g/mL · 0.5 g/mL at 25 °C (lit.)
refractive index
1.56 · 1.5600
storage temp.
Room Temperature
solubility
polar oganic solvents: soluble
form
powder

Safety & regulation

Safety data

F
3-10
PPE
Eyeshields, Gloves, type N95 (US)
wgk
1
tsca
TSCA listed
rtecs
NF9050000
hs_code
39129000

Chemistry & industry

Applications · 6 items

DescriptionHydroxypropyl cellulose (HPC) is a derivative of cellulose being soluble in both water and organic acid. It is excellent in trapping water and preventing water loss. It can be used to treat diseases associated with insufficient tear production such as keratoconjunctivitis sicca, recurrent corneal erosions, decreased corneal sensitivity, and exposure and neuroparalytic keratitis. It is also used as a lubricant of artificial eyes. It can also be used as a thickener, an emulsion stabilizer and binder. Moreover, it can be used as a sieving matrix for DNA separation through capillary and microchip electrophoresis. It is also the major ingredient of Cellugel, which is used in book conservation.

DescriptionHydroxypropyl cellulose is a cellulose ether containing hydroxypropyl substitution. It occurs as a white powder. It is soluble in water and in certain organic solvents. It may contain a suitable anticaking agent.

UsesHydroxypropyl Cellulose is used in the synthesis of nanoparticle carriers for drug delivery.

UsesAs emulsifier, stabilizer, whipping aid, protective colloid, film former or thickener in foods; as binder in ceramics and glazes; in hair and cosmetic Preparations; in vacuum-formed containers and blow-molded bottles; as suspending agent in PVC polymerization. Pharmaceutic aid (tablet coating agent).

UsesHydroxypropyl Cellulose is a gum that is nonionic water-soluble cellulose, obtained from the reaction of alkali cellulose with propyl- ene oxide at high temperatures and pressures. it is soluble in water below 40°c, is precipitated as a floc between 40°c and 45°c, and is insoluble above 45°c. the precipitation is reversible with the origi- nal viscosity being restored upon cooling below 40°c and stirring. it is used in whipped toppings as a stabilizing and foaming aid; in edible food coatings as a glaze and oil/oxygen barrier; and in fabri- cated foods as a binder. typical usage level is 0.05–1.0%.

General DescriptionHydroxypropyl cellulose (HPC) is biocompatible in nature and exhibits low critical solution temperature (LCST). It has been reported to be prepared by reacting cellulose with alkali, producing alkali cellulose which is consecutively reacted with propylene oxide. HPC is soluble in water at lower than RT. Viscosity behaves inversely to rise in temperature.

Suppliers50 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
西安清言生物科技有限责任公司15339027915

Additional notes

DefinitionA cellulose ether with hydroxypropyl substitution.

Related reactions

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