Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178750987Generated: October 23, 2026

Levothyroxine EP Impurity B

Levothyroxine Impurity B · Levothyroxine EP Impurity B · Levothyroxine Impurity-B (Crude) · Levothyroxine imp B (Mono chloro) · Monochlorotriiodothyronine (Impurity-B) · Levothyroxine EP Impurity-B (Mono chloro) · Levothyroxine?EP?Impurity?B (3-Chloro Thyroxine) · (S)-2-amino-3-(4-(3-chloro-4-hydroxy-5-iodophenoxy)

https://huagongshe.com/en/chemical/178750987

Levothyroxine EP Impurity B molecular structure

Identifiers & Physical Properties

CAS No.1628720-66-0
Molecular formulaC15H11ClI3NO4
Average molar mass685.42 g/mol
SMILESN[C@@H](Cc1cc(I)c(Oc2cc(Cl)c(O)c(I)c2)c(I)c1)C(=O)O
InChIKeyMQUDMFHNJQNOJT-LBPRGKRZSA-N

Chemical & Physical Properties

XLogP2.3
Topological polar surface area92.8
Hydrogen bond donors3
Hydrogen bond acceptors5
Rotatable bonds5
Heavy atoms24
Formal charge0
Complexity435
Boiling point567.9±50.0 °C(Predicted)
Density2.408±0.06 g/cm3(Predicted)
pKa (acidity coefficient)2.12±0.30(Predicted)

Applications & Uses

Uses

3-Chloro Thyroxine is an impurity of Thyroxine (T425600(P)), which is one of the thyroid hormones involved in the maintenance of metabolic homeostasis.