[(2R,3R,4R,5R,6S)-4,5-dihydroxy-6-[[(1R,3R,4R,5S,8S)-3-[(2R,3S,4R,5R,6S)-5-hydroxy-2-(hydroxymethyl)-6-[[(1R,3S,4R,5S,8S)-3-hydroxy-4-sulfonatooxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-3-sulfonatooxyoxan-4-yl]oxy-4-sulfonatooxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-2-(hydroxymethyl)oxan-3-yl] sulfate
IOTA-CARRAGEENAN · TS 150 · MOSS IRISH · IRISH MOSS · Aids031651 · SeaSpen PF · Isish Moss · Aids-031651
![[(2R,3R,4R,5R,6S)-4,5-dihydroxy-6-[[(1R,3R,4R,5S,8S)-3-[(2R,3S,4R,5R,6S)-5-hydroxy-2-(hydroxymethyl)-6-[[(1R,3S,4R,5S,8S)-3-hydroxy-4-sulfonatooxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-3-sulfonatooxyoxan-4-yl]oxy-4-sulfonatooxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-2-(hydroxymethyl)oxan-3-yl] sulfate molecular structure](/img/chemical/178790089.png)
Identifiers & Physical Properties
| CAS No. | 9062-07-1 |
|---|---|
| Molecular formula | C24H34O31S4-4 |
| Average molar mass | 946.8 g/mol |
| SMILES | O=S(=O)([O-])O[C@@H]1[C@H]2OC[C@@H](O[C@@H]1O)[C@@H]2O[C@@H]1O[C@H](CO)[C@H](OS(=O)(=O)[O-])[C@H](O[C@H]2O[C@@H]3CO[C@@H]([C@H]3O[C@@H]3O[C@H](CO)[C@H](OS(=O)(=O)[O-])[C@H](O)[C@H]3O)[C@H]2OS(=O)(=O)[O-])[C@H]1O |
| InChIKey | QIDSWKFAPCTSKL-RRQHLKGPSA-J |
| ChEBI | CHEBI:37168 |
Chemical & Physical Properties
| XLogP | -9.4 |
|---|---|
| Topological polar surface area | 504 |
| Hydrogen bond donors | 6 |
| Hydrogen bond acceptors | 31 |
| Rotatable bonds | 12 |
| Heavy atoms | 59 |
| Formal charge | -4 |
| Complexity | 1,840 |
| Storage conditions | room temp |
| Solubility | H2O: 5 mg/mL hot, solublePartially soluble in water, Soluble in hot water. Insoluble in ethanol, in hot concentrated salt solutions. |
| Physical state | Powder |
| Color | White to Pale Brown |
| pH | 8.0 - 10.5 |
| Biological source | algae (Eucheuma spinosum) |
| Viscosity | 5.0 to 20.0 m Pa-s(0.3 %, H2O, 25 ℃) |
| Merck | 14,1858 |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChIKey | QIDSWKFAPCTSKL-RRQHLKGPSA-J |
| FDA UNII | 3582R1F52W |
| UNSPSC Code | 12352201 |
| NACRES | NA.25 |
| Personal protective equipment (PPE) | Eyeshields, Faceshields, Gloves, type N95 (US) |
| Safety statements (S) | 24/25 |
| Water hazard class (WGK) | 2 |
| F | 3 |
| Customs code | 13023990 |
| Storage class | 11 - Combustible Solids |
Safety & Regulations
| F | 3 |
|---|---|
| Personal protective equipment (PPE) | Eyeshields, Faceshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 2 |
| Customs code | 13023990 |
| Safety statements (S) | 24/25 |
| Storage class | 11 - Combustible Solids |
Applications & Uses
Uses
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-,and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
Uses
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ-carrageenans have varying degrees of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities. ι-Carrageenan may be used to help define the role of carrageenan sulfation levels in physicochemical, biochemical, biological and pharmacological responses.
Uses
Carrageenan, iota type is used as a stabilizer, for suspending cocoa in chocolate manufacture, and to clarify beverages.Carrageenans are used commercially as thickeners and stabilizing agents.
General Description
Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.