HuagongsheHuagongshe Chemistry Print Report · For research reference only
CID 126456000
Ivermectin impurity 17 · IverMectin Monosaccharide · Ivermectin Impurity 17 (IverMectin B1 Monosaccharide) · DihydroaverMectin B1 Monosaccharide, IverMectin B1 Monosaccharide
Identifiers & Physical Properties
| CAS No. | 123997-64-8 |
|---|---|
| Molecular formula | C41H62O11 |
| Average molar mass | 730.9 g/mol |
| SMILES | CC[C@H](C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@H](C/C=C(\C)[C@@H](O[C@H]3C[C@H](OC)[C@@H](O)[C@H](C)O3)[C@@H](C)/C=C/C=C3\CO[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O1)C34O)O2 |
| InChIKey | IDRWWNAYSYRQBV-RANFAGGCSA-N |
Chemical & Physical Properties
| XLogP | 3.7 |
|---|---|
| Topological polar surface area | 142 |
| Hydrogen bond donors | 3 |
| Hydrogen bond acceptors | 11 |
| Rotatable bonds | 5 |
| Heavy atoms | 52 |
| Formal charge | 0 |
| Complexity | 1,410 |
Applications & Uses
Uses
Ivermectin monosaccharide is a semi-synthetic potent inhibitor of nematode larval development.
Uses
:Ivermectin B1a monosaccharide is a semi-synthetic produced by selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance.