Basic information
- Standard SMILES
Cc1cnc(C(=O)O)c[n+]1[O-]- InChIKey
DJQOOSBJCLSSEY-UHFFFAOYSA-N- Molecular formula
- C6H6N2O3
- Average molar mass
- 154.12 g/mol
Overview
5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid is a pyrazinecarboxylic acid.
Names & identifiers
- Preferred name
- Acipimox
- IUPAC
- 5-methyl-4-oxidopyrazin-4-ium-2-carboxylic acid
- English name
- Acipimox-d4
- Molecular formula
- C6H6N2O3
- Molecular weight
- 154.12344
Names & synonyms
ACIPIMOX51037-30-0OlbetamOlbemox5-methylpyrazine-2-carboxylic acid 4-oxide5-Methylpyrazinecarboxylic acid 4-oxide5-methyl-4-oxidopyrazin-4-ium-2-carboxylic acidDTXSID2046202NSC-759818K9AY9IR2SDDTXCID00262025-CARBOXY-2-METHYLPYRAZIN-1-IUM-1-OLATE
Show more names
K 9321-d4OlbetaM-d4OlbeMox-d4Acipimox-d4[2H4]-Acipimox5-Methylpyrazinecarboxylic Acid 4-Oxide-d45-Methyl-2-pyrazinecarboxylic Acid 4-Oxide-d4
AcipimoxumRefChem:552678C10AD06256-928-35-Carboxy-2-methylpyrazine 1-oxideMFCD008657572-CARBOXY-5-METHYLPYRAZINE 4-OXIDEACIPIMOX [WHO-DD]
Database identifiers
- CAS
1246816-28-3- ChEMBL
CHEMBL345714- ChEBI
CHEBI:94688- UNII
- K9AY9IR2SD
- EC Number
- 256-928-3
- Nikkaji
- J10.290C
Properties
Computed structural properties
- XLogP
- -1
- Topological polar surface area
- 75.7 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 11
- Formal charge
- 0
- Complexity
- 162
Experimental & physicochemical properties
Drugs
Pharmaceuticals -> Antilipidemics
Pharmaceuticals -> Listed in ZINC15
Physicochemical properties
- Melting point
- 170 °C · >170°C (dec.)
- storage temp.
- -20 °C · -20°C Freezer
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- Off-White to Light Beige
Safety & regulation
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 41.7% (30 of 72) of reports.
Warning
H319 (58.3%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)
Aggregated GHS information provided per 72 reports by companies from 3 notifications to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesEye Irrit. 2A (58.3%)
Chemistry & industry
Pharmacology
ATC Code
C10AD06
C - Cardiovascular system
QC - Cardiovascular system
Mechanism of ActionAcipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL.
MeSH Pharmacological ClassificationSubstances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
Applications
UsesLabelled antilipemic.
Suppliers7 total
艾吉析科技（上海）有限公司17717235263 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
常州翔龙医药科技有限公司18915873328 18915873328 · [email protected]
深圳振强药物研发有限公司+86-0755-66853366 +86-13670046396 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
梯尔希（南京）药物研发有限公司18012923235 18012923235 · [email protected]
上海皓鸿生物医药科技有限公司400-8210725 4008210725 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Linked notes
Loading…