Kanamycin A Sulfate

HCID 178956684CAS 133-92-6
Substructure searchFind similar structures

Basic information

Standard SMILES
NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O.O=S(=O)(O)O
InChIKey
OOYGSFOGFJDDHP-KMCOLRRFSA-N
Molecular formula
C18H38N4O15S
Average molar mass
582.6 g/mol

Overview

Kanamycin A sulfate is an aminoglycoside sulfate salt. It has a role as a geroprotector and an antibacterial drug. It contains a kanamycin A.

Names & identifiers

Preferred name
Kanamycin A Sulfate
IUPAC
(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
English name
KANAMYCIN SULFATE
Molecular formula
C18H38N4O15S
Molecular weight
582.58

Names & synonyms

Kanamycin A sulfateKanamycin A sulphateDTXSID1047524J80EX28SMQEINECS 223-347-1(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acidCHEBI:6109DTXCID9027524KANAMYCIN A SULFATE [MI]KANAMYCIN SULFATE [USP-RS]KANAMYCIN SULFATE [USP MONOGRAPH]KANAMYCIN MONOSULFATE [EP MONOGRAPH]
Show more names
KANAMYCIN MONOSULFATEKANAMYCIN SULPHATEKANAMYCIN ACID SULFATEKAMYCINKANAMYCIN SULFATE WHITEKANAMYCIN MONO SULPHATEKANAMYCIN A SULFATE SALTKANAMYCIN MONOSULFATE SALTKanamycin sulfate soluble powder 12%KANAMYCIN SULFATE, STREPTOMYCES KANAMYCETICUS
KANAMYCIN SULFATE (USP-RS)KANAMYCIN SULFATE (USP MONOGRAPH)D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->4))-2-DEOXY-, SULFATE (1:1) (SALT)D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->4))-2-DEOXY-, SULPHATE (1:1) (SALT)D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl(1->4))-2-deoxy-, sulfate (1:1) (salt)KANAMYCIN MONOSULFATE (EP MONOGRAPH)Kanaplex(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-((1R,2R,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy-2-hydroxycyclohexyl)oxyoxane-3,4,5-triol;sulfuric acid

Database identifiers

CAS
133-92-6
ChEMBL
CHEMBL1446
ChEBI
CHEBI:6109
UNII
J80EX28SMQ
EC Number
223-347-1、613-414-7

Properties

Computed structural properties

Topological polar surface area
366 Ų
Hydrogen bond donors
13
Hydrogen bond acceptors
19
Rotatable bonds
6
Heavy atoms
38

Experimental & physicochemical properties

Human Drugs · 2 items

FDA approved drugs -> Active ingredient

FDA approved drugs -> Active ingredient

Animal DrugsActive Ingredients (Kanamycin Sulfate) -> FDA Greenbook
Collision Cross Section221.1 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Physicochemical properties

storage temp.
2 · 2-8°C
solubility
2 O: · H2O: 10-50 mg/mL As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 5 days.
form
powder
PH
pH (50g/l, 25℃) : 6.0～7.5
Safety Statements
22 · 22-24/25
WGK Germany
3 · 3

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 1% (1 of 96) of reports.

Danger

H360 (69.8%): May damage fertility or the unborn child [Danger Reproductive toxicity]

P203, P260, P264, P270, P273, P280, P318, P319, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 96 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

Hazard information

Hazard Classes and Categories · 2 items

Repr. 1B (69.8%)

Repr. 1B (100%)

Safety data

wgk
3
rtecs
NZ3225030
safety_code
22-24/25

Chemistry & industry

Uses & manufacturing

Use ClassificationAnimal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

Applications

UsesAntibacterial Kantrex (Apothecon).

Suppliers22 total

江苏瑞点药业有限公司15896106238 · [email protected]
Hebei Zhuanglai Chemical Trading Co Ltd+86-16264648883 · [email protected]
山东海舟生物工程有限公司130-0567-0367 13006570367 · [email protected]
Hebei ZB Gamay Biological Technology Co.,Ltd+86-13933180921 · [email protected]
杭州鼎燕化工有限公司13588754826 13588754826 · [email protected]

Additional notes

DefinitionChEBI: Kanamycin A sulfate is an aminoglycoside sulfate salt. It has a role as an antibacterial drug and a geroprotector. It contains a kanamycin A.

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