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Basic information
- Standard SMILES
CC(C)=CCCC(C)=CCCC(C)=CC(O)P(=O)(O)O- InChIKey
MONZTFSZTWQCKH-UHFFFAOYSA-N- Molecular formula
- C15H27O4P
- Average molar mass
- 302.351 g/mol
- Monoisotopic mass
- 302.16469597
Names & identifiers
- Preferred name
- (1-hydroxy-3,7,11-trimethyldodeca-2,6,10-trienyl)phosphonic acid
- IUPAC
- (1-Hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl)phosphonic acid
- English name
- alpha-Hydroxyfarnesylphosphonic acid
- Molecular formula
- C15H27O4P
- Molecular weight
- 302.35
Names & synonyms
HFPAα-hydroxy Farnesyl Phosphonic AcidHYDROXYFARNESYL PHOSPHATEMONZTFSZTWQCKH-IJFRVEDASA-NA-hydroxyfarnesylphosphonic acidalpha-Hydroxyfarnesylphosphonic acidalpha-Hydroxyfarnesylphosphonic aicdALPHA-HYDROXYFARNESYL PHOSPHONIC ACID ETHANOL SOLUTIONαhydroxy Farnesyl Phosphonic Acid,α hydroxy Farnesyl Phosphonic Acid(+/-)-1-HYDROXY-3,7,11-TRIMETHYL-2E,6E,10-DODECATRIENE-1-PHOSPHONIC ACID
Database identifiers
- CAS
148796-53-6- PubChem CID
- 2106
- DTXSID
DTXSID50274355
Properties
Physicochemical properties
- storage temp.
- 20 °C · −20°C
- solubility
- 10 mM · 10 mM Na2CO3: freely soluble; ETOH: >25 mg/ml; PBS pH 7.2: <25 μg/ml
- form
- A crystalline solid
- Hazard Codes
- F,Xi
- Risk Statements
- 11 · 11-36/37/38
- Safety Statements
- 16 · 16-26-36-7
- RIDADR
- 1170 · UN 1170 3/PG 2
- WGK Germany
- 3 · 3
Safety & regulation
Safety data
- wgk
- 3
- ridadr
- UN 1170 3/PG 2
- risk_code
- 11-36/37/38
- hazard_code
- F,Xi
- safety_code
- 16-26-36-7
Chemistry & industry
Applications
Descriptionα-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.
Usesα-hydroxy Farnesyl phosphonic acid is a nonhydrolyzable analog of farnesyl pyrophosphate which acts as a competitive inhibitor of farnesyl transferase (FTase). At concentrations greater than 1 μM, α-hydroxy farnesyl phosphonic acid inhibits the processing of Ras in Ha-ras-transformed NIH3T3 cells.
Suppliers6 total
MedBio脉铂医药021-69568360 18916172912 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226 · [email protected]
上海宏叶生物科技有限公司400-9205774 400-920-5774 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
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Linked notes
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