1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt)

HCID 23692652CAS 90693-88-2

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Basic information

Standard SMILES
CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@H](COP(=O)([O-])OC[C@H](N)C(=O)O)OC(=O)CCCCCCC/C=C\CCCCCCCC.[Na+]
InChIKey
RRLDZFIFYLDDLI-OLZOWLLTNA-N
Molecular formula
C42H79NNaO10P
Average molar mass
812.05 g/mol

Names & identifiers

Preferred name
1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt)
English name
1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt)
Molecular formula
C42H79NNaO10P
Molecular weight
812.05

Names & synonyms

18:1 PS (DOPS)DOPS (18:1 PS)1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)1,2-Dioctadecenoyl-sn-glycero-3-PhosphoserineDioyl phosphatidylserine (sodium salt) (DOPS-NA)1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium1,2-Dioleoyl-sn-glycero-3-phosphoserine sodium salt (DOPS Na)sodium O-(((R)-2,3-bis(oleoyloxy)propoxy)oxidophosphoryl)-L-serinate1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (SODIUM SALT)18:1 PS (DOPS)1,2-di - (9Z-octadecanoyl) - sn-glycero-3-phosphoyl-L-serine sodium salt

Database identifiers

CAS
90693-88-2
PubChem CID
23692652
UNII
ZBE12XT39T

Properties

Physicochemical properties

storage temp.
-20 °C · Store at -20°C
solubility
10 mg/ml · Chloroform: 10 mg/ml
form
A crystalline solid
color
Light yellow to orange
Water Solubility
soluble (Insoluble in ethanol and DMSO, soluble in Chloroform:Methanol:Water (65:25:4) at 5mg/mL)
InChIKey
RRLDZFIFYLDDLI-OLZOWLLTNA-N

Safety & regulation

Safety data

wgk
WGK 3
Signal word
Warning
Symbol(GHS)
GHS07
Storage Class
13 - Non Combustible Solids
Hazard statements
H302-H315-H319-H335
Precautionary statements
P261-P280-P301+P312-P302+P352-P305+P351+P338

Chemistry & industry

Applications · 2 items

Description1,2-Dioleoyl-sn-glycero-3-PS (DOPS) is a phospholipid containing oleic acid (Item Nos. 90260 | 24659) at the sn-1 and sn-2 positions, respectively. Nanovesicles composed of DOPS and the lysosomal protein saposin C (SapC) are cytotoxic to SK-MEL-28 cells in vitro and decrease tumor volume in a squamous cell carcinoma mouse xenograft model. DOPS has been used in the formation of unilamellar vesicles to study the effect of curvature on membrane structure and in the formation of supported lipid bilayers to study the effects of various support materials on lipid redistribution between membrane leaflets.

Uses1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) is a lipid being studied in the assembly and long-term stability of solid supported lipid bilayers from artificial and natural lipid mixtures.

Suppliers50 total

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖北威德利化学试剂有限公司181-6332-1995 18062128043 · [email protected]
Shochem(Shanghai) Co.,Ltd86-21-50800795 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
咸宁深蓝生物医药研发有限公司18171815831 · [email protected]

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