HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boron tribromide
BBr3 · tribromoborane · BORON BROMIDE · tribromuredebore · SILVER TRIFLUOROMETHANE · Boron tribroMide, 1.0 M solution in CH2Cl2 · Tronite · Bortribromid
Identifiers & Physical Properties
| CAS No. | 10294-33-4 |
|---|---|
| Molecular formula | BBr3 |
| Average molar mass | 250.53 g/mol |
| Monoisotopic mass | 247.7643167 g/mol |
| SMILES | BrB(Br)Br |
| InChIKey | ILAHWRKJUDSMFH-UHFFFAOYSA-N |
| PubChem CID | 25134 |
| EC No. | 233-657-9 |
| DTXSID | DTXSID4065028 |
Chemical & Physical Properties
| Topological polar surface area | 0 |
|---|---|
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 0 |
| Rotatable bonds | 0 |
| Heavy atoms | 4 |
| Formal charge | 0 |
| Complexity | 8 |
| Chemical classes | Toxic Gases & Vapors -> Other Toxic Gases & VaporsCorrosives |
| SpringerMaterials Properties | dielectric constant |
| Odor | Sharp, irritating odorPungent |
| Density | 2.645 at 68 °F (USCG, 1999) - Denser than waterwill sink2.6 g/cu cmRelative density (water = 1): 2.72.64 at 68 °F2.650 @ 0°C(65 °F): 2.642.60 g/mL at 20 °C(lit.) |
| Viscosity | 0.731 cP at 75 °F (liquid) |
| Color/Form | Colorless, fuming liquid |
| Solubility | Decomposes (NIOSH, 2024)Soluble in carbon tetrachloride, sulfur dioxide (liquid), sulfur dichloridemoderately soluble in methylcyclohexaneSolubility in water: reactionMiscible with ethanol and carbon tetrachloride.Reacts with water. |
| Corrosivity | Strongly attacks metals and woodCorrosive to rubber and bakeliteCorrosive to tissue |
| Boiling point | 196 °F at 760 mmHg (USCG, 1999)91.3 °C91 °C194 °F91.3 °C @760 [mm Hg]~90 °C |
| Decomposition | On decomposition, /one mole of/ boron tribromide would be expected to produce three moles of hydrogen bromide.When heated to decomposition, emits toxic fumes of /bromides/.The toxic action of the halogenated borons is considerably influenced by their decomposition products (hydrofluoric acid-, fluoboric acid-, hydrochloric acid-). /Halogenated borons/ |
| Melting point | -51 °F (USCG, 1999)-46 °C−46 °C(lit.) |
| Vapor density | Relative vapor density (air = 1): 8.68.6 (vs air) |
| Vapor pressure | 40 mm Hg ( 14 °C) |
| Flash point | 30 °F |
| Refractive index | 1.4340 |
| Storage conditions | Poison room |
| Physical state | Solution |
| Specific gravity | 2.65 |
| Color | colorless |
| Specific heat capacity | Cp(gas): 0.27 J/(g·K), at 25℃ |
| Sensitivity | Moisture Sensitive |
| Merck | 14,1347 |
| Dielectric constant | 2.6(0℃) |
| Stability | Stable, but reacts violently with water. |
| InChI | 1S/BBr3/c2-1(3)4 |
| InChIKey | ILAHWRKJUDSMFH-UHFFFAOYSA-N |
| SMILES | BrB(Br)Br |
| CAS DataBase Reference | 10294-33-4(CAS DataBase Reference) |
| EWG's Food Scores | 2 |
| FDA UNII | A453DV9339 |
| EPA Substance Registry System | Boron tribromide (10294-33-4) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
| GHS pictogram | GHS05,GHS06,GHS08,GHS09 |
| Signal word | Danger |
| GHS hazard statements | H300+H330-H314-H370-H372-H373-H341-H350-H336-H411-H290 |
| GHS precautionary statements | P501-P273-P270-P202-P260-P234-P201-P271-P264-P280-P284-P390-P391-P308+P311-P303+P361+P353-P301+P330+P331-P363-P301+P310+P330-P304+P340+P310-P305+P351+P338+P310-P403+P233-P406-P405 |
| Target organs | Central nervous system |
| Personal protective equipment (PPE) | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Hazard symbols | T+,C,F,N |
| Risk statements (R) | 14-26/28-35-40-62-11-67-65-50/53-37-51/53-48/20 |
| Safety statements (S) | 9-26-28-36/37/39-45-23-33-16-62-61-60 |
| Occupational exposure limit (OEL) | Ceiling: 1 ppm (10 mg/m3) |
| UN transport number | UN 2692 |
| Water hazard class (WGK) | 3 |
| RTECS number | ED7400000 |
| F | 10-21 |
| TSCA inventory status | TSCA listed |
| Hazard class | 8Acute Tox. 2 InhalationAcute Tox. 2 OralCarc. 2Eye Dam. 1Skin Corr. 1ASTOT SE 3 |
| Packing group | I |
| Customs code | 28129090 |
| Storage class | 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials |
| Hazardous substances data | 10294-33-4(Hazardous Substances Data) |
| REACH registrations | Active |
| Excepted quantities | Forbidden |
Safety & Regulations
| GHS classification | DangerH300: Fatal if swallowed [Danger Acute toxicity, oral]P260, P264, P270, P271, P280, P284, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P320, P321, P330, P363, P403+P233, P405, and P501 (click each P-code to see the statement)H300 (100%): Fatal if swallowed [Danger Acute toxicity, oral] |
|---|---|
| Hazards Identification | Toxic/poison by inhalation (TIH/PIH) |
| Regulatory information | Chemical: Borane, tribromo-Status: Active Update: 18-09-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/31639Boron tribromide: HSNO Approval: HSR002916 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| Other safety information | IMAP assessments - Borane, tribromo-: Human health tier I assessment |
| DOT label | Corrosive Poison Inhalation Hazard |
| Fire hazards | Special Hazards of Combustion Products: Toxic fumes of the chemical or hydrogen bromide may form in fires. (USCG, 1999)· Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.Not combustible. Heating will cause rise in pressure with risk of bursting. Risk of fire and explosion on contact with water. Risk of fire and explosion as a result of decomposition when heated. |
| Fire potential | Not flammable |
| Health hazards | Inhalation causes severe irritation of mucous membranes. Ingestion causes burns of mouth and stomach. Contact with eyes or skin causes severe burns. (USCG, 1999)· TOXIC and/or CORROSIVEinhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. |
| Hazards summary | Liquid will burn skin[CHRIS] Toxic effects are similar to those of hydrogen bromide (which is released when BBr3 reacts violently with water). [ACGIH] A corrosive that can cause pulmonary edema[ICSC] |
| DOT ID and guide | 2692 157 |
| Reactive group | Halogenating Agents |
| EC classification | Symbol: T+, CR: 14-26/28-35S: (1/2)-9-26-28-36/37/39-45 |
| UN classification | UN Hazard Class: 8UN Pack Group: I |
| Fire fighting | Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]:In case of fire in the surroundings, use appropriate extinguishing media. NO water. In case of fire: keep drums, etc., cool by spraying with water. NO direct contact with water. |
| First aid measures | Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.First rinse with plenty of water for at least 15 minutes, then remove contaminated clothes and rinse again. Refer for medical attention .First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Do NOT induce vomiting. Refer for medical attention . |
| Accidental release measures | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| First aid | Excerpt from NIOSH Pocket Guide for Boron tribromide:General First Aid:(General first aid procedures) |
| Safe storage | Separated from incompatible materials. See Chemical Dangers. Cool. Dry. Ventilation along the floor. |
| Exposure control and personal protection | · Wear positive pressure self-contained breathing apparatus (SCBA).TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016]. |
| Fire fighting procedures | Extinguish fire using agent suitable for surrounding fire. Use dry chemical, or carbon dioxide. DO NOT use water. Violent reaction may result.If material involved in fire: Use dry chemical, dry sand, or carbon dioxide. Do not use water on material itself. If large quantities of combustibles are involved, use water in flooding quantities as spray and fog. Use water spray to knock-down vapors. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. |
| Storage conditions | Separate from alkalies, oxidizing materials, alcohols, ethers, alkali metals, phosphorus, wood. Store in a cool, dry, well-ventilated location.Separated from incompatible materials. ...Cool. Dry. Ventilation along the floor.Keep container in a well ventilated place.Usual shipping containers: Glass bottle or metal can inside wooden boxsteel or nickel cylinders, tanks. Packaged under nitrogen gas.Store under dry inert aatmosphere. Reacts violently with water, alcohols. |
| Cleanup methods | Releases may require isolation or evacuation. Keep water away from release. Stop or control the leak, if this can be done without undue risk. Approach release from upwind. Absorb in noncombustible material for proper disposal.If material not involed in fire: Neutralize spilled material with crushed limestone, soda ash, or lime.Small quantities of boron tribromide may be destroyed by cautious addition to a large volume of ... water containing ice.It is ... highly dangerous to wash glass ampoules of boron tribromide with water under any circumstances.For more Cleanup Methods (Complete) data for BORON TRIBROMIDE (6 total), please visit the HSDB record page. |
| Nonfire spill response | Excerpt from ERG Guide 157 [Substances - Toxic and/or Corrosive (Non-Combustible / Water-Sensitive)]: |
| Disposal methods | SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air qualitypotential migration in soil or watereffects on animal and plant lifeand conformance with environmental and public health regulations.SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a permitted wastewater treatment facility is acceptable only after review by the governing authority and assurance that "pass through" violations will not occur. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must be evaluated in accordance with EPA 40 CFR Part 261, specifically Subpart B, in order to determine the appropriate local, state and federal requirements for disposal. |
| Spillage disposal | Evacuate danger area! Consult an expert! Personal protection: chemical protection suit including self-contained breathing apparatus. Ventilation. NEVER direct water jet on liquid. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. |
| Treatment | EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. |
| Target organs | Eyes, skin, respiratory systemCentral nervous system |
| Health effects | Bromine vapour causes irritation and direct damage to the mucous membranes. Elemental bromine also burns the skin. The bromide ion is a central nervous system depressant and chronic exposure produces neuronal effects. This is called bromism and can result in central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia, loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, delirium, aggressiveness, and psychoses. (L625, L626, L627) |
| Adverse effects | Dermatotoxin - Skin burns. |
| Exposure routes | The substance can be absorbed into the body by inhalation and by ingestion.inhalation, ingestion, skin and/or eye contactOral (L626)inhalation (L626)dermal (L626) |
| Toxicity summary | Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and produce tissue damage. In additon, the formation of hydrobromic and bromic acids will result in secondary irritation. The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in the in actions of neurotransmitters and transport systems, thus affecting numerous synaptic processes. (L626, L627, A543) |
| Signs and Symptoms | Cough. Shortness of breath. Sore throat. Burning sensation. Laboured breathing. Symptoms may be delayed.Redness. Skin burns. Pain. Blisters.Redness. Pain. Severe deep burns.Abdominal cramps. Burning sensation. Weakness. Diarrhoea. Vomiting. Abdominal pain. Shock or collapse.irritation eyes, skin, respiratory systemeye, skin burnsdyspnea (breathing difficulty), pulmonary edemaBromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways, coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous system depressant producing ataxia, slurred speech, tremor, nausea, vomiting, lethargy, dizziness, visual disturbances, unsteadiness, headaches, impaired memory and concentration, disorientation and hallucinations. This is called bromism. (L626, L627) |
| Medical Surveillance | No specific considerations are needed for boric acid or borates except for general health and liver and kidney function. /Boric acid and borates/ |
| Human Toxicity Excerpts | /SIGNS AND SYMPTOMS/ Boron tribromide ... is severely corrosive to the eye. In one instance it has caused severe localized scarring of cornea and conjunctiva./SIGNS AND SYMPTOMS/ Very toxic by inhalation and if swallowed. Causes severe burns./SIGNS AND SYMPTOMS/ Potential symptoms of overexposure are ... dyspnea, pulmonary edema./SIGNS AND SYMPTOMS/ EFFECTS OF SHORT-TERM EXPOSURE: The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation may cause lung edema.For more Human Toxicity Excerpts (Complete) data for BORON TRIBROMIDE (7 total), please visit the HSDB record page. |
| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
| Probable Routes of Human Exposure | NIOSH (NOES Survey 1981-1983) has statistically estimated that 1,554 workers (878 of these are female) are potentially exposed to boron tribromide(1). Occupational exposure to boron tribromide may occur through inhalation and dermal contact with this compound at workplaces where boron tribromide is produced or used(SRC).Industrial exposures ... occur from release ... into the worker atmosphere as well as from production & handling ... /Boron halides/ |
| Environmental Fate/Exposure Summary | The chemistry of boron is dominated by its tendency to form stable bonds with electronegative atoms, especially oxygen. Reduced boron compounds (halides, hydrides, alkyls and aryls) tend to oxidize and hydrolyze readily, and would be expected to be converted into various boron-oxide compounds in the environment. Inorganic boron compounds are nonvolatile and would not be expected to volatilize from moist or dry soil surfaces. (SRC) |
| DHS Chemicals of Interest (COI) | Boron tribromide12.6745A Commercial GradeA Placarded AmountWeapons of Mass Effect chemical material that, if stolen or diverted, can be converted into weapons using simple chemistry, equipment, or techniques. |
| State drinking water guidelines | (CA) CALIFORNIA 1000 ug/L /Boron/(NH) NEW HAMPSHIRE 630 ug/L /Boron/(ME) MAINE 1,400 ug/L /Boron/(MN) MINNESOTA 1,000 ug/L /Boron/(WI) WISCONSIN 960 ug/L /Boron/ |
| Federal drinking water guidelines | EPA 600 ug/L /Boron/ |
| F | 10-21 |
| Occupational exposure limit (OEL) | Ceiling: 1 ppm (10 mg/m3) |
| Personal protective equipment (PPE) | Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter |
| Water hazard class (WGK) | 3 |
| TSCA inventory status | TSCA listed |
| RTECS number | ED7400000 |
| UN transport number | UN 2692 |
| Customs code | 28129090 |
| Risk statements (R) | 14-26/28-35-40-62-11-67-65-50/53-37-51/53-48/20 |
| Signal word | Danger |
| GHS pictogram | GHS05,GHS06,GHS08,GHS09 |
| Hazard symbols | T+,C,F,N |
| Safety statements (S) | 9-26-28-36/37/39-45-23-33-16-62-61-60 |
| Hazard class | 8Acute Tox. 2 InhalationAcute Tox. 2 OralCarc. 2Eye Dam. 1Skin Corr. 1ASTOT SE 3 |
| Storage class | 6.1A - Combustible acute toxic Cat. 1 and 2very toxic hazardous materials |
| Packing group | I |
| GHS hazard statements | H300+H330-H314-H370-H372-H373-H341-H350-H336-H411-H290 |
| Excepted quantities | Forbidden |
| REACH registrations | Active |
| GHS precautionary statements | P501-P273-P270-P202-P260-P234-P201-P271-P264-P280-P284-P390-P391-P308+P311-P303+P361+P353-P301+P330+P331-P363-P301+P310+P330-P304+P340+P310-P305+P351+P338+P310-P403+P233-P406-P405 |
| Hazardous substances data | 10294-33-4(Hazardous Substances Data) |
Applications & Uses
General Description
Boron tribromide is commercially available and is a strong Lewis acid. It is an excellent demethylating or dealkylating agent for ethers, often in the production of pharmaceuticals. boron tribromide lewis structure Additionally, it also finds applications in olefin polymerisation and in Friedel–Crafts chemistry as a Lewis acid catalyst. The electronics industry uses boron tribromide as a boron source in pre-deposition processes for doping in the manufacture of semiconductors. Boron tribromide is a colourless, fuming liquid compound containing boron and bromine. It is usually made by heating boron trioxide with carbon in the presence of bromine: this generates free boron that reacts vigorously with the bromine. Boron tribromide is used extensively in industries associated with pharmaceutical manufacturing, image processing, semiconductor doping, plasma etching, and photovoltaic manufacturing and as a reagent for different chemical processes.
Uses
as the major chemical raw material of the production of caustic soda, soda ash, widely used in alkali industry. As a semiconductor silicon doping source, it can be used for preparation of high purity boron and organic boron compound. Trona is mainly used for making soda ash, caustic soda, soda, and other products. Soda ash is an important industrial raw material, widely used in glass, chemicals, light industry, textile, dyeing, metallurgy, petroleum processing, pharmaceuticals, food and so on. Caustic soda is mainly used for rayon, paper, dyes, soap, plastics, pharmaceuticals, agricultural chemicals and so on. Baking soda is mainly used in food, plastics, rubber, pharmaceutical, printing and dyeing, tanning, soaking seeds and other areas. As a dopant materials of semiconductor, catalyst, intermediate and brominated agent of organic synthesis, It is a raw material for producing high purity boron and other organic boron compound. Used in organic synthesis and preparation for high purity boron. As catalyst, intermediates and Brominating agents for organic synthesis, raw materials for manufacturing high purity boron and other organic boron compound.
Description
Boron tribromide is a colorless, fumingliquid. Molecular weight=250.57. Boiling point=90℃;Freezing/Melting point=-46℃; Vapor pressure=53 hPaat 14℃. Hazard Identification (based on NFPA-704 MRating System): Health 3, Flammability 0, Reactivity 2.Soluble in water; dangerous reaction.
Uses
Catalyst in manufacture of diborane, ultrahigh-purity boron, and semiconductors
Uses
Boron Tribromide is used as a reagent in the synthesis of 8-hydroxyquinolato compounds used as electron transport materials in EL devices. It is also used in the demethylation of aryl methyl ethers by boron tribromide.
Uses
manufacture of diborane; ultra high purity boron. Reagent for cleavage of ethers, amines, thiols; addition of allenes and alkynes.
General Description
A colorless, fuming liquid with a pungent odor. Boiling point 194°F. Freezing point -51°F. Very toxic by inhalation. Corrosive to metals and tissue.